Metabolic Adaptation in Indigenous Siberian Populations
نویسندگان
چکیده
Previous research has suggested that arctic populations have elevated metabolic rates in response to their cold, marginal climate. Recent studies of indigenous Siberian groups have confirmed these earlier findings and have shed light on the mechanisms through which northern populations adapt to their environments. Indigenous Siberians show significant elevations in basal metabolic rate compared with reference values. Total energy expenditure is variable across Siberian groups and is correlated with levels of acculturation. Siberian populations appear to have adapted to cold stress through both short-term acclimatization and genetic adaptations, with thyroid hormones playing an important role in shaping metabolic responses. Elevated metabolic rates also have important consequences for health and may contribute to the low serum lipid levels observed in Siberian groups. Further research is needed to elucidate the underlying mechanisms of metabolic adaptation and their implications for ongoing health changes among indigenous Siberians. 451 A nn u. R ev . A nt hr op ol . 2 00 5. 34 :4 51 -4 71 . D ow nl oa de d fr om a rj ou rn al s. an nu al re vi ew s. or g by D r. J os h Sn od gr as s on 0 9/ 25 /0 5. F or p er so na l u se o nl y. AR254-AN34-23 ARI 7 September 2005 21:27 BMR: basal metabolic rate TEE: total energy expenditure
منابع مشابه
Adaptive dimensions of health research among indigenous Siberians.
Present evidence suggests that modern humans were the first hominid species to successfully colonize high-latitude environments (> or =55 degrees N). Given evidence for a recent (<200,000 years) lower latitude naissance of modern humans, the global dispersal and successful settlement of arctic and subarctic regions represent an unprecedented adaptive shift. This adaptive shift, which included c...
متن کاملGenome-Wide Analysis of Cold Adaptation in Indigenous Siberian Populations
Following the dispersal out of Africa, where hominins evolved in warm environments for millions of years, our species has colonised different climate zones of the world, including high latitudes and cold environments. The extent to which human habitation in (sub-)Arctic regions has been enabled by cultural buffering, short-term acclimatization and genetic adaptations is not clearly understood. ...
متن کاملBasal metabolic rate in the Yakut (Sakha) of Siberia.
Human indigenous circumpolar populations have elevated basal metabolic rates (BMRs) relative to predicted values; this metabolic elevation has been postulated to be a physiological adaptation to chronic and severe cold stress. The present study examines BMR in the Yakut, an indigenous high-latitude population from the Sakha Republic of Russia to determine (1) whether the Yakut show evidence of ...
متن کاملExome Sequencing Provides Evidence of Polygenic Adaptation to a Fat-Rich Animal Diet in Indigenous Siberian Populations.
Siberia is one of the coldest environments on Earth and has great seasonal temperature variation. Long-term settlement in northern Siberia undoubtedly required biological adaptation to severe cold stress, dramatic variation in photoperiod, and limited food resources. In addition, recent archeological studies show that humans first occupied Siberia at least 45,000 years ago; yet our understandin...
متن کامل